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. 2020 Jan 21;9(2):e013755. doi: 10.1161/JAHA.119.013755

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© 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Correlation between radiotherapy (A) and discrete myocardial fibrosis (LGE, red arrows; B). Cardiac magnetic resonance imaging‐detectable diffuse fibrosis (ECV; C) corresponding to biopsy‐proven fibrosis (D), after esophageal cancer radiotherapy. Specifically, histopathologically, interstitial fibrosis (yellow arrow) and myocardial degeneration such as irregular arrangement (white arrow) or vacuolar changes (blue arrow) are seen. Adapted with permission from Mukai‐Yatagai et al.59 Copyright ©2018, Elsevier. ECV indicates extracellular volume; LGE, late gadolinium enhancement.