Table 3.

Predictors of 5‐Year Mortality on Cox Proportional‐Hazards Analysis

	Adjusted HR	HR 95% CI	P Value
Demographics and comorbidities
Age	1.029	1.025 to 1.032	<0.001
BMI	0.982	0.977 to 0.988	<0.001
Charlson comorbidity index	1.147	1.128 to 1.166	<0.001
Previous cancer diagnosis	0.834	0.755 to 0.921	<0.001
Previous lung disease diagnosis	1.143	1.046 to 1.248	0.003
Illness severity
APACHE‐III score	1.006	1.003 to 1.009	<0.001
Maximum week 1 SOFA	1.051	1.030 to 1.073	<0.001
Admission vital signs
Admission shock index	1.393	1.213 to 1.601	<0.001
Respiratory rate	1.010	1.003 to 1.017	0.004
CICU therapies and procedures
Invasive ventilator	0.815	0.703 to 0.945	0.007
New dialysis start	1.629	1.195 to 2.219	0.002
IABP	0.727	0.624 to 0.846	<0.001
Coronary angiogram	0.851	0.781 to 0.927	<0.001
Discharge diagnoses
HF	1.406	1.291 to 1.530	<0.001
Sepsis	1.322	1.150 to 1.519	<0.001
Admission laboratory values
Serum bicarbonate	1.031	1.022 to 1.040	<0.001
BUN	1.007	1.005 to 1.010	<0.001
Admission sodium group
Hyponatremia vs normal	1.281	1.168 to 1.406	<0.001
Hypernatremia vs normal	1.357	1.122 to 1.642	0.002
Hyponatremia vs hypernatremia	0.944	0.772 to 1.155	0.58

Only predictors with P<0.01 are shown. Additional predictors included in the model with P≥0.01 were noninvasive ventilator use, oxygen saturation, creatinine, CRRT, dialysis, cardiac arrest, admission MAP, PCI, respiratory failure. APACHE indicates Acute Physiology and Chronic Health Evaluation; ACS, acute coronary syndrome; BMI, body mass index; BUN, blood urea nitrogen; CICU, cardiac intensive care unit; CRRT, continuous renal replacement therapy; HF, heart failure; HR, hazard ratio; IABP, intra‐aortic balloon pump; MAP, mean arterial pressure; PCI, percutaneous intervention; SOFA, Sequential Organ Failure Assessment.