Figure 1.

Slug is chiefly expressed by vascular smooth muscle cells that adopted a macrophage‐like phenotype in the neointima of type V atherosclerotic lesions of human carotid arteries. Serial sections of a representative human type V atherosclerotic lesion obtained from a carotid endarterectomy sample counterstained with hematoxylin and immunolabeled with an anti‐Slug, an anti‐CD68, an anti–smooth muscle actin (SMA), or an anti–smooth muscle–specific myosin heavy chain (SMMHC). Images of right panels are obtained at a magnification of ×10. Proteins of interest appearing in brown are indicated by black arrows. The images are representative of serial sections from 4 different patients. a indicates adventitia, l, lumen; m, media. *Lipid core. **Fibrous cap.