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The cardiac loop and systolic anterior motion (SAM). Because of the U‐turn redirection from the cardiac loop, flow turns around mitral valve. Because of the intimate relation of the inflow and outflow portions of the left ventricle, this arrangement is prone to fail, because of relatively small anatomic perturbations that cause SAM. In obstructive hypertrophic cardiomyopathy, the mitral valve is swept into the septum by the pushing force of flow.1, 2, 3, 4, 5
