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. 2020 Feb 3;9(3):e013808. doi: 10.1161/JAHA.119.013808

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© 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Median left ventricular dimensions correlated with number of variants of uncertain significance (VUSs) in the cardiac actionable genes in 94 patients with a cardiomyopathy diagnosis. A, Left ventricular internal diameter in diastole (LVIDd) corrected for body surface area (BSA) over 14 years of echocardiographic data derived from the electronic health record. Those with a VUS or VUSs had an increase in LVIDd, corrected for BSA. B, Data for left ventricular internal diameter in systole (LVIDs) corrected for BSA, gathered over the same time frame as (A). P values for slope difference estimates are shown in Table 4.