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. 2020 Feb 3;9(3):e014035. doi: 10.1161/JAHA.119.014035

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© 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Effects of temperature on coronary vasodilation. A, Left and right parts of the bar chart show similar percent change in diameter after administration of endothelium‐independent vasodilator (nitroglycerin) along rewarming and moderate hypothermia (MoHT) protocols, respectively. B, Right bars (MoHT protocol) show an effect of temperature on endothelium‐dependent vasodilation with a significant increase in the percent change of diameter after administering bradykinin at 32°C time point. Left part of the bar chart (rewarming protocol) shows no differences in coronary vasodilation after bradykinin administration in the rewarming protocol. C, Bar chart depicts no statistical differences in the percent change in diameter at hyperemia (ATP) between time points in either protocol.