Table 2.
Univariate and multivariate analysis of Overall Survival (OS) in PDAC patients (n = 166)
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CI | p-Value | HR | 95%CI | p-Value | |
| Age | 0.702 | 0.485–1.017 | 0.062 | |||
| Gender | 0.825 | 0.582–1.171 | 0.283 | |||
| Differentiation (moderately or poor vs. well) | 1.245 | 0.772–2.008 | 0.369 | |||
| T stage (T3 or T4 vs. T1 or T2) | 1.396 | 0.981–1.986 | 0.064 | |||
| TNM stage (AJCC) (stage II or stage III vs. stage I) | 3.250 | 2.003–5.274 | 0.001** | 1.888 | 1.001–3.559 | 0.050 |
| Lymphatic metastasis | 2.842 | 1.928–4.189 | 0.001** | 1.900 | 1.149–3.140 | 0.012* |
| PLACT1 expression | 1.645 | 1.154–2.345 | 0.006** | 1.460 | 1.017–2.096 | 0.040* |
Abbreviations: HR hazard ratio, 95%CI 95% confidence interval, T stage tumor stage, TNM tumor node metastasis. Cox regression analysis, *p < 0.05, **p < 0.01