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. 2020 Feb 12;35(1):639–649. doi: 10.1080/14756366.2020.1726342

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Compounds IC₅₀ determination against L. braziliensis promastigotes cells and their cytotoxic effect against mammalian cells. (A, B) L. braziliensis promastigotes cell viability was determined as described in Material and Methods section (Equation (2). (C, D) Compounds cytotoxic activity against Balb/C 3T3 clone A31 mouse fibroblast cells. IC₅₀ for each compound concentration was fitted by a concentration-dependent equation.