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. 2020 Feb 12;35(1):639–649. doi: 10.1080/14756366.2020.1726342

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Concentration–response curves of compounds against LbHsp90 ATPase activity inhibition. The ATPase activity inhibition of LbHsp90 was determined as described in Material and Methods section. Concentration-response curve of four compounds, namely (A) Glb08, (B) Glb15, (C) Glb23 and (D) GA. The absolute IC₅₀ value was determined by nonlinear regression analysis employing GraphPad Prism 6 software.