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. 2020 Jan 21;11(4):648–658. doi: 10.1021/acschemneuro.9b00682

Table 2. Reliability of K1 Values between “Test” and “Retest” Scans in All the Brain Regions.

regions K1 Test ± SD K1 Retest ± SD Rel. Diff. K1 (%) TRV K1 (%) CV (%) K1 test CV (%) K1 Retest ICC K1
amygdala 0.24 ± 0.04 0.21 ± 0.04 –7.75 8.07 15.61 20.88 0.287
cerebellum 0.34 ± 0.03 0.3 ± 0.04 –7.86 8.18 8.65 17.44 0.15
corpus callosum 0.23 ± 0.04 0.19 ± 0.03 –7.91 8.24 15.83 24.14 0.521
medial geniculate 0.26 ± 0.04a 0.23 ± 0.03a –6.52 6.74 13.42 19.60 0.741
mesencephalic region 0.34 ± 0.03 0.29 ± 0.02 –9.95 10.47 9.48 14.89 –0.04
septum 0.25 ± 0.03a 0.2 ± 0.03a –11.07 11.72 12.72 26.20 0.537
superior colliculus 0.32 ± 0.04 0.28 ± 0.04 –5.90 6.08 12.26 18.83 0.493
striatum 0.22 ± 0.04 0.19 ± 0.03 –7.89 8.22 16.70 23.79 0.616
cortex 0.22 ± 0.03 0.2 ± 0.04 –4.01 4.09 13.44 23.11 0.692
hippocampus 0.24 ± 0.03 0.21 ± 0.04 –8.86 9.28 14.34 22.80 0.555
hypothalamus 0.3 ± 0.04 0.26 ± 0.05 –8.94 9.35 13.96 19.04 0.688
mid brain 0.33 ± 0.05 0.28 ± 0.03 –8.67 9.06 14.66 16.59 0.128
brainstem 0.38 ± 0.04 0.34 ± 0.04 –7.98 8.31 10.01 14.78 –0.021
thalamus 0.27 ± 0.04 0.23 ± 0.03 –7.53 7.82 15.02 20.94 0.428
basal ganglia 0.24 ± 0.04 0.2 ± 0.03 –9.18 9.62 15.40 21.83 0.37
whole brain 0.26 ± 0.03 0.23 ± 0.04 –6.65 6.88 12.38 20.42 0.522
mean ± SD     –7.92 ± 1.66 8.26 ± 1.79 13.37 ± 2.36 20.33 ± 3.32 0.42 ± 0.25
a

Significant differences between “Test” and “Retest” scan (p < 0.05).