Table 1.
Micelles | Feed drug ratio | Size (nm) | PDI | aStability (h) |
---|---|---|---|---|
mPEG-PLA | – | 20.3 ± 0.42 | 0.091 | – |
DTX/mPEG-PLA | 7.5 | 27.6 ± 0.56 | 0.089 | <0.5 |
5.0 | 25.8 ± 0.64 | 0.078 | <1 | |
2.5 | 23.6 ± 0.23 | 0.056 | <2 | |
mPEG-PLA-Phe(Boc) | – | 23.4 ± 0.64 | 0.094 | – |
DTX/mPEG-PLA-Phe(Boc) | 7.5 | 18.7 ± 0.38 | 0.075 | <2 |
5.0 | 17.4 ± 0.58 | 0.062 | >24 | |
2.5 | 17.2 ± 0.33 | 0.047 | >72 |
Stability: time of precipitation appeared.