Table 2.
ROC analysis of the diagnostic efficiency of differential long non-coding ribonucleic acids (lncRNAs) (RP11-33A14.1, RP11-423H2.3, and LAMTOR5-AS1) and serum prostate-specific antigen (PSA) in prostate cancer (PCa) patients and benign prostatic hyperplasia (BPH) controls.
Biomarker | Sensitivity (%) | Specificity (%) | AUC (95% CI) | P-value |
---|---|---|---|---|
RP11-33A14.1 | 60.4 | 70.2 | 0.697 (0.506–0.734) | 0.001 |
RP11-423H2.3 | 56.2 | 61.4 | 0.620 (0.506–0.734) | 0.035 |
LAMTOR5-AS1 | 58.3 | 64.9 | 0.641 (0.531–0.751) | 0.013 |
LAMTOR5-AS1 + RP11-33A14.1+RP11-423H2.3 | 77.1 | 63.2 | 0.754 (0.655–0.854) | <0.001 |
PSA | 95.8 | 84.2 | 0.974 (0.946–0.998) | <0.001 |
LAMTOR5-AS1 + RP11-33A14.1+RP11-423H2.3 + PSA | 97.9 | 84.2 | 0.984 (0.964–1.004) | <0.001 |