Table 1. Distribution of mcr-1 in CREs during 2014–2019.
| Strain species | No. of strains (1 April 2014–20 February 2017) | No. of strains (21 February 2017–30 April 2019) | P-value* | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CRE | blaKPC positive | blaNDM positive | CPE | mcr-1 |
mcr-1 carrying rate (%) |
CRE | blaKPC positive | blaNDM positive | CPE | mcr-1 |
mcr-1 carrying rate (%) |
||
| K. pneumoniae | 740 | 554 | 121 | 705 | 0 | 0 | 394 | 309 | 32 | 384 | 0 | 0 | – |
| E. coli | 235 | 85 | 132 | 221 | 5 | 2.13% | 141 | 62 | 73 | 137 | 9 | 6.38% | 0.035 |
| Enterobacter cloacae | 132 | 19 | 81 | 105 | 0 | 0 | 52 | 9 | 39 | 52 | 0 | 0 | – |
| Serratia marcescens | 21 | 6 | 14 | 21 | 0 | 0 | 20 | 7 | 0 | 7 | 0 | 0 | – |
| Enterobacter aerogenes | 26 | 6 | 16 | 26 | 0 | 0 | 19 | 15 | 1 | 16 | 0 | 0 | – |
| Citrobacter freundii | 21 | 2 | 13 | 21 | 0 | 0 | 8 | 3 | 5 | 8 | 0 | 0 | – |
| K. oxytoca | 24 | 7 | 10 | 24 | 0 | 0 | 7 | 2 | 3 | 5 | 0 | 0 | – |
| Other species | 16 | 7 | 7 | 12 | 0 | 0 | 12 | 6 | 5 | 11 | 0 | 0 | – |
| Total | 1215 | 686 | 394 | 1135 | 5 | 0.41% | 653 | 413 | 158 | 620 | 9 | 1.38% | 0.042 |
CRE, carbapenem-resistant Enterobacteriaceae; CPE, carbapenem-producing Enterobacteriacease.
*Differences between groups were assessed by Pearson chi-square and continuity correction. P-value in bold indicates statistical significance.