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. 2020 Jan-Mar;11(1):25–29. doi: 10.4103/japtr.JAPTR_74_19

Table 3.

Fractional inhibitory concentration, fractional inhibitory concentration index, and outcome of interactions between Rosmarinus officinalis essential oil and carvacrol against Bacillus subtilis

Components MIC % (v/v)
FIC% (v/v) FICI Outcome
Alone In combination
EO 0. 0625 0.031 0.496 0.527 Partial synergy
Carvacrol 0.125 0.0039 0.0312
EO 0. 0625 0.015 0.24 0.36 Synergistic
Carvacrol 0.125 0.015 0.12
EO 0. 0625 0.007 0.112 0.36 Synergistic
Carvacrol 0.125 0.031 0.248
EO 0. 0625 0.0019 0.030 0.526 Partial synergy
Carvacrol 0.125 0.062 0.496

FIC: Fractional inhibitory concentration, MIC: Minimum inhibitory concentration, EO: Essential oil, FICI: Fractional inhibitory concentration index