Table 2.

A1c Months and complications, in ascending order of A1c Months, in the EDC 1965–1980 diabetes diagnosis subcohort (n = 434)

Complication	A1c Months at the time of incidence, mean (SD) and median complication (p25, p75)	Hazard ratio per 100 A1c Months (95% CI)*	P value
Microalbuminuria (n at risk = 234**, 99 events)	844 (423)	1.17 (1.11, 1.23)	<0.0001
	782 (573, 1,043)
Proliferative retinopathy (n at risk = 347**, 192 events)	907 (383)	1.14 (1.10, 1.18)	<0.0001
	866 (620, 1,187)
CDSP (n at risk = 325**, 127 events)	963 (444)	1.12 (1.07, 1.16)	<0.0001
	919 (629, 1,246)
CAD (n at risk = 413**, 98 events)	1,068 (469)	1.09 (1.04, 1.14)	0.0004
	986 (725, 1,398)
Overt nephropathy (n at risk = 314**, 61 events)	1,139 (537)	1.20 (1.14, 1.27)	<0.0001
	1,035 (744, 1,471)
ESRD (n at risk = 429**, 53 events)	1,265 (495)	1.18 (1.12, 1.25)	<0.0001
	1,274 (873, 1,618)

p25, 25th percentile; p75, 75th percentile.

^*Estimated using time-varying Cox models.

^**Prevalent cases at baseline excluded from analysis.