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. 2020 Dec 11;69(3):413–423. doi: 10.2337/db19-0942

Figure 2.

Figure 2

IGF1 decreases with increased duration of type 1 diabetes. A: Disease onset for the BRI cohort was at significantly older age than for the UFDI cohort with established type 1 diabetes (Mann-Whitney U test). B: IGF1 percentile for age and sex decreases with increasing disease duration in cross-sectional established type 1 diabetes cohorts from UFDI and BRI. C: IGF2 percentile is not associated with disease duration in either cohort. Data are overlaid with best fit lines (solid) and 95% CI (dashed lines). Spearman correlation: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.