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. 2020 Jan 7;23(1):53–58. doi: 10.4103/aca.ACA_156_18

Table 4.

Comparisons of cardiac surgery associated acute kidney injury positive and negative cases statistically tested by unpaired t-test

Parameters CSA-AKI positive (n=66) CSA-AKI negative (n=68) P


Mean (SD)/n (%)# 95% CI of mean Mean (SD)/n (%)# 95% CI of mean
Male# 32 (48.48) 28 (41.18) 0.4873
Female# 34 (51.52) 40 (58.82) 0.4873
Age (years) 39.66 (13.15) 36.43-42.90 36.35 (11.71) 33.51-39.19 0.1256
Weight (kg) 50.95 (7.81) 49.03-52.87 48.80 (8.66) 46.71-50.90 0.1349
Height (cm) 159.80 (7.90) 157.86-161.75 156.61 (8.70) 154.51-158.73 0.0284
eGFR (ml/min/1.73m2) 74.12 (22.57) 68.57-79.67 66.40 (18.49) 61.92-70.88 0.0319
Preoperative creatinine (mg %) 0.91 (0.22) 0.85-0.96 1.02 (0.22) 0.96-1.07 0.0047
Preoperative blood urea (mg %) 29.75 (14.70) 26.14-33.37 30.36 (17.66) 26.08-34.64 0.8286
CPB time (min) 103.71 (40.50) 93.74-113.68 89.30 (43.38) 78.79-99.82 0.0492
X-clamp (min) 79.62 (34.53) 71.12-88.11 66.76 (37.30) 57.72-75.80 0.0405
POD 1 urine output 1.15 (0.28) 1.08-1.28 1.25 (0.41) 1.15-1.35 0.1208
POD 2 urine output 1.17 (0.37) 1.08-1.27 1.21 (0.37) 1.12-1.30 0.5596
POD 3 urine output 1.21 (0.41) 1.11-1.31 1.20 (0.28) 1.14-1.27 0.9644
Serum creatinine (mg %)
 POD 1 1.27 (0.37) 1.18-1.36 1.03 (0.24) 0.97-1.09 <0.0001
 POD 2 1.36 (0.41) 1.26-1.47 1.00 (0.23) 0.95-1.06 <0.0001
 POD 3 1.31 (0.47) 1.19-1.43 0.94 (0.23) 0.89-1.00 <0.0001
Blood urea (mg %)
 POD 1 41.15 (14.59) 37.56-44.74 36.10 (13.17) 32.91-39.29 0.0374
 POD 2 46.86 (14.99) 43.17-50.55 37.41 (13.71) 34.09-40.73 0.0002
 POD 3 48.10 (16.42) 44.03-52.18 34.52 (13.76) 31.16-37.88 <0.0001

#Fisher’s exact test, CSA-AKI: Cardiac surgery associated acute kidney injury, eGFR: Estimated glomerular filtration rate, SD: Standard deviation, CI: Confidence interval, CPB: Cardiopulmonary bypass, X-clamp: Aortic cross clamp, POD: Postoperative day