Table 6.
Clinical parameters and cardiac surgery associated acute kidney injury trend with estimated glomerular filtration rate analyzed by Chi-square test of independence and Fisher’s exact test
| Parameters | Preoperative eGFR (ml/min/1.73m2 BSA), mean (SD) | P | |||
|---|---|---|---|---|---|
| >100 (n=13) | >80-100 (n=30) | >60-80 (n=38) | 40-60 (n=53) | ||
| Age (years) | 34.0 (9.66) | 36.83 (13.54) | 35.15 (10.98) | 41.64 (12.89) | 0.0431 |
| Weight (kg) | 56.0 (9.87) | 54.06 (9.93) | 48.10 (6.36) | 47.24 (6.38) | <0.0001 |
| Height (cm) | 161.46 (8.63) | 160.10 (12.05) | 158.50 (7.46) | 156.07 (5.89) | 0.0745 |
| Base serum creatinine (mg %) | 0.73 (0.20) | 0.83 (0.16) | 0.94 (0.17) | 1.12 (0.19) | <0.0001 |
| Preoperative eGFR (ml/min/1.73 m2) | 113.22 (8.75) | 87.85 (6.03) | 68.61 (4.92) | 50.81 (5.80) | <0.0001 |
| Baseline blood urea (mg %) | 22.76 (8.89) | 27.03 (18.63) | 29.76 (12.57) | 33.79 (17.76) | 0.0885 |
| CPB time (min) | 84.00 (46.67) | 95.7 (53.57) | 95.78 (34.81) | 100.28 (39.87) | 0.6712 |
| Aortic clamp time (min) | 56.07 (32.73) | 73.56 (45.17) | 73.26 (32.06) | 76.88 (34.43) | 0.3339 |
| CSA-AKI, n (%) | 9 (69.23) | 17 (56.67) | 19 (50.00) | 21 (39.62) | 0.1943* |
| OR$ (P)$ | Control | 0.58 (0.51) | 0.44 (0.33) | 0.29 (0.06) | |
| 95% CI of OR$ | 0.14-2.31 | 0.11-1.69 | 0.07-1.07 | ||
*Chi-square test of independence, $Fisher’s exact test. CSA-AKI: Cardiac surgery associated acute kidney injury, eGFR: Estimated glomerular filtration rate, SD: Standard deviation, CI: Confidence interval, CPB: Cardiopulmonary bypass, OR: Odds ratio, BSA: Body surface area