Figure 3.

Common features of endocytic pathways [73]. Endocytosis requires a specific cell membrane composition at the site of uptake (A) [72,74–76] and starts with the recognition of the cargo at the cell membrane (B). Subsequently, membrane bending takes place to form a vesicle (C) [72–73,77–78,84]. Lastly, the vesicle is cleaved from the cell membrane via different mechanisms, which can involve various cellular components (e.g., actin and dynamin, here depicted as lines and circles, respectively) (D) [79–80].