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. 2019 Dec 10;15(6):1140–1149. doi: 10.4103/1673-5374.270316

Figure 11.

Figure 11

Possible neuroprotective mechanism of FSK in ICV-PPA intoxicated autism.

5-HT: 5-Hydroxytryptamine; AC: adenyl cyclase; Ach: acetylcholine; ATP: adenosine triphosphate; cAMP: cyclic adenosine monophosphate; BDNF: brain-derived neurotrophic factor; cAMP: cyclic adenosine monophosphate; CO-Q10: coenzyme Q10; CREB: cyclic AMP response element binding protein; DA: dopamine; FSK: forskolin; ICV-PPA: intracerebroventricular propionic acid; NA: noradrenaline; NGF: nerve growth factor; PKA: protein kinase A; RNS: reactive nitrogen species; ROS: reactive oxygen species.