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. 2019 Dec 10;15(6):1102–1110. doi: 10.4103/1673-5374.270418

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Up- and downregulated proteins in the KD group.

(A) Several proteins, such as S100-A8, acyl-CoA-binding proteins, peroxiredoxin-1, and vimentin, were upregulated in the KD group compared with the NC group. S100-A8 plays a prominent role in the regulation of inflammatory processes, immune response, and antioxidant activity. We found that protein levels of both S100-A8 and S100-A9 were upregulated two-fold in the KD group compared with the NC group. (B) Alpha-1-antitrypsin 1-1, 1-2, 1-4, and 1-5, along with stathmin and neurofilaments (medium and heavy), were downregulated in the KD group compared with the NC group. KD: Knockdown; NC: negative control.