Supplementary Table 5.

Multivariate Cox regression analysis of the impact of metastatic sites on cancer-specific survival when using metastasis of bone, lung, liver as the reference group.

Features	Level	Hazard ratio (95% CI)	P-value
Metastatic sites	Bone	Ref
	Lung	1.022 (0.854–1.223)	0.815
	Liver	1.310 (1.047–1.640)	0.018
	Brain	1.877 (1.378–2.556)	<0.001
Metastatic sites	Lung	Ref
	Bone	0.979 (0.818–1.171)	0.815
	Brain	1.837 (1.346–2.507)	<0.001
	Liver	1.282 (1.021–1.610)	0.032
Metastatic sites	Liver	Ref
	Lung	0.780 (0.621–0.979)	0.032
	Bone	0.763 (0.610–0.955)	0.018
	Brain	1.432 (1.022–2.008)	0.037