Supplementary Table 6.
Univariate and multivariate Cox regression analyses of prognostic factors for overall survival in patients with only bone metastases.
| Features | Level | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
|
| |||||
| Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | ||
| Age (years) | <65 | Ref | Ref | ||
| ≥65 | 1.564 (1.262–1.939) | <0.001 | 1.356 (1.083–1.696) | 0.008 | |
|
| |||||
| Race | White | Ref | – | ||
| Black | 1.014 (0.793–1.298) | 0.911 | – | – | |
| Others | 0.971 (0.614–1.536) | 0.901 | – | – | |
|
| |||||
| Grade | G1/G2 | Ref | – | ||
| G3/G4 | 0.988 (0.751–1.299) | 0.929 | – | – | |
|
| |||||
| Tumor size (cm) | ≤2 | Ref | – | ||
| 2–5 | 0.880 (0.638–1.212) | 0.433 | – | – | |
| >5 | 1.032 (0.743–1.434) | 0.852 | – | – | |
|
| |||||
| Node stage | Node negative | Ref | – | ||
| Node positive | 1.161 (0.899–1.500) | 0.253 | – | – | |
|
| |||||
| Surgery of the primary | No | Ref | Ref | ||
| Yes | 0.422 (0.336–0.531) | <0.001 | 0.463 (0.367–0.584) | <0.001 | |
|
| |||||
| Chemotherapy | No/unknown | Ref | Ref | ||
| Yes | 0.451 (0.359–0.567) | <0.001 | 0.581 (0.454–0.743) | <0.001 | |
|
| |||||
| Insurance | Yes | Ref | Ref | ||
| No | 2.542 (1.454–4.444) | 0.001 | 2.450 (1.382–4.343) | 0.002 | |
|
| |||||
| Marital status | Married | Ref | Ref | ||
| Unmarried | 1.344 (1.079–1.675) | 0.008 | 1.155 (0.923–1.445) | 0.207 | |