Supplementary Table 8.
Univariate and multivariate Cox regression analyses of prognostic factors for overall survival in patients with only liver metastases.
| Features | Level | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
|
| |||||
| Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | ||
| Age (years) | <65 | Ref | Ref | ||
| ≥65 | 1.700 (1.211–2.388) | 0.002 | 1.306 (0.902–1.892) | 0.158 | |
|
| |||||
| Race | White | Ref | – | – | |
| Black | 1.190 (0.833–1.698) | 0.339 | – | – | |
| Others | 1.188 (0.550–2.565) | 0.661 | – | – | |
|
| |||||
| Grade | G1/G2 | Ref | – | – | |
| G3/G4 | 1.110 (0.707–1.743) | 0.650 | – | – | |
|
| |||||
| Tumor size (cm) | ≤2 | Ref | – | – | |
| 2–5 | 1.614 (0.962–2.708) | 0.070 | – | – | |
| >5 | 1.342 (0.793–2.273) | 0.273 | – | – | |
|
| |||||
| Node stage | Node negative | Ref | – | – | |
| Node positive | 0.754 (0.515–1.103) | 0.146 | – | – | |
|
| |||||
| Surgery of the primary | No | Ref | Ref | ||
| Yes | 0.549 (0.397–0.760) | <0.001 | 0.594 (0.426–0.828) | 0.002 | |
|
| |||||
| Chemotherapy | No/unknown | Ref | Ref | ||
| Yes | 0.279 (0.191–0.409) | <0.001 | 0.314 (0.204–0.484) | <0.001 | |
|
| |||||
| Insurance | Yes | Ref | Ref | ||
| No | 3.347 (1.537–7.287) | 0.002 | 2.323 (1.007–5.326) | 0.048 | |
|
| |||||
| Marital status | Married | Ref | Ref | 0.088 | |
| Unmarried | 1.424 (1.022–1.983) | 0.037 | 1.338 (0.958–1.869) | ||