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. 2020 Feb 14;11:67. doi: 10.3389/fphar.2020.00067

Figure 4.

Figure 4

Molecular weights (MWs) and octanol/water partition coefficients (logP) were visualized for all drug data sets [(A) drug-induced cholestasis, (B): drug-induced cirrhosis, (C) drug-induced hepatitis, and (D) drug-induced steatosis]. Dotted lines were drawn where logP was0 and molecular weight was 500. The majority of DILI-positive drugs had MWs less than 500 and logP values higher than 0.