Figure 4.
Molecular weights (MWs) and octanol/water partition coefficients (logP) were visualized for all drug data sets [(A) drug-induced cholestasis, (B): drug-induced cirrhosis, (C) drug-induced hepatitis, and (D) drug-induced steatosis]. Dotted lines were drawn where logP was0 and molecular weight was 500. The majority of DILI-positive drugs had MWs less than 500 and logP values higher than 0.