Table 2:

Adverse Events on Vedolizumab

Event	Patients with inflammatory bowel disease (n=27)
Adverse event – Non-infectious
Neurological complaints (n=4)	4 Total - 1 Paraesthesia - 1 migraine - 2 mild tremor
Pruritis	1 total
Rheumatological	2 Total - 1 new onset arthralgia - 1 leg cramps
Infusion related reaction	1 infusion reaction*
Cancer	No cancer documented
Constipation	2 total
Perianal disease	1 Total - 1 worsening perianal fistula
Fatigue	1 total
Oro-facial complications	1 total - 1 gum sensitivity
Any serious non-infectious event*	1 total
Adverse event – Infections
Enteric infection	2 total - 1 viral enteritis* - 1 CMV and C. difficile colitis – colectomy*
Sino-pulmonary infections	1 sinusitis
Post-operative complications	2 total   -  1 delayed perineal healing   -  1 mucocutaneous separation of stoma
Miscellaneous	1 UTI
Any serious infection*	4 total

^*A serious adverse event or infection was defined as any adverse event when leading to treatment interruption, antibiotic therapy, hospitalization, disability or persistent damage, colectomy or death