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. Author manuscript; available in PMC: 2020 Apr 2.
Published in final edited form as: Sci Transl Med. 2019 Oct 2;11(512):eaaw3639. doi: 10.1126/scitranslmed.aaw3639

Fig. 8. Inhibition of TRPM2 blocks JNK activation in HK-2 cells.

Fig. 8.

(A) Immunoblot for TRPM2 in HK-2 cell lysate.

(B) Immunoblot of H2O2-dependent JNK activation following treatment with 25 μM ACA in the left panel, quantitated in the right panel.

Scatter plots are mean ± standard deviation. * denotes statistical significance (p<0.05) *** denotes statistical significance (p<0.001). **** denotes statistical significance (p<0.0001). kDa = kiloDaltons.