Table 6. Effect of biflavonoid on the levels of TBARS and HP in the liver of control and experimental rats.
Groups | TBARS (mmol/g tissue) | Hydroperoxide (mmol/g tissue) |
---|---|---|
Control | 0.81 ±0.07 | 63.42 ± 5.37 |
Normal + Biflavonoid (80mg/kg b w) | 0.85 ± 0.08 | 60.79 ± 4.90 |
Diabetes Induced | 1.92 ± 0.11b | 132.39 ± 9.14b |
Diabetes + Biflavonoid (80mg/kg b w) | 1.25 ± 0.19c | 75.52 ± 7.39c |
Diabetes + Metformin (500mg/kg b w) | 1.14 ± 0.11 | 72.10 ± 0.11 |
Values are given as mean ± SD for six animals in each group.
Values are considered significantly different at P < 0.05 with post hoc LSD test *P < 0.05.
The symbols a, b c and d also represent the statistical significance at p < 0.05.
a Control vs Drug control rats(normal rats received biflavonoid alone).
b Control vs Diabetic rats.
c Diabetic control rats.vs Diabetic rats treated with biflavonoid (80mg/kg).
d Diabetic rats treated with biflavonoid (80 mg/kg) vs Diabetic rats treated with Metformin (500 mg/kg).