Table 8. Effect of biflavonoid on the activities of non enzymic antioxidant in the liver of control and experimental rats.
Group | Vit C(µmol/mg tissue) | Vit E(µmol/mg tissue) | Reduced glutathione (GSH) (µmol/mg tissue) |
---|---|---|---|
Control | 2.37 ± 0.23 | 1.61 ± 0.15 | 57.34 ± 4.33 |
Normal + Biflavonoid (80mg/kg b w) | 3.02 ± 0.30 | 2.16 ± 0.20 | 59.68 ± 4.22 |
Diabetes Induced Diabetes + Biflavonoid (80mg/kg b w) | 1.12 ± 0.12b | 0.86 ± 0.07b | 34.16 ± 2.47b |
2.17 ± 0.21c | 1.57 ± 0.11c | 47.86 ± 3.07c | |
Diabetes + Metformin (500mg/kg b w) | 2.58 ± 0.25 | 1.88 ± 0.15 | 50.05 ± 3.18 |
Values are considered significantly different at P < 0.05 with post hoc LSD test *P < 0.05.
The symbols a, b c and d also represent the statistical significance at p < 0.05.
a Control vs Drug control rats(normal rats received biflavonoid alone).
b Control vs Diabetic rats.
c Diabetic control rats.vs Diabetic rats treated with biflavonoid (80 mg/kg).
d Diabetic rats treated with biflavonoid (80 mg/kg) vs Diabetic rats treated with Metformin (500 mg/kg).