Figure 1:

Mover-Stayer latent transition analysis model with baseline age, sex, and education as covariates, and dementia as a distal clinical outcome. In the model the same ten latent class indicators are measured at three time-points (u1-u10, u11-u20, u21-u30). The model assumes measurement invariance across time for the ten latent class indicators. C1, C2, and C3 indicate the latent classes at Times 1, 2, and 3. C is the higher-order mover-stayer latent variable. Time-invariant covariates and a distal outcome were related to the higher-order mover-stayer class.