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. 2020 Feb 14;8:1. doi: 10.3389/fchem.2020.00001

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Copyright © 2020 Huang, Huang, Zhang, Zhuang, Liu, Su, Ye, Xu, Kuang and Xie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Schematic illustration of ICG-liposome-based PTT on mice. Primary tumor growth profile of MC-38-bearing (B) and CT26-bearing (C) mice from each group. Distant tumor outgrowth curves of double MC-38 tumor-bearing mice (D) and double CT-26 tumor-bearing mice (E) in which the primary tumor was left untreated or PTT-treated. (F) CD8 T cells infiltration of each group in the MC-38 tumor microenvironment on day 3 and 12 after treatment was examined by immunofluorescence. n = 6 in each group. Data are presented as means ± SD. Statistical significance was calculated by Student's t-test: ***P < 0.001, **P < 0.01, *P < 0.05.