Table 2.
Diagnostic accuracy of CT protocol versus reference MI per patient and per vessel
| Sensitivity, % (95% CI) | Specificity, % (95% CI) | PPV, % (95% CI) | NPV, % (95% CI) | Accuracy, % (95% CI) | |
|---|---|---|---|---|---|
| Per patient | |||||
| DCE | 79 (58–93) | 88 (68–97) | 86 (65–97) | 81 (61–93) | 83 (70–93) |
| Rest | 67 (45–84) | 92 (73–99)* | 89 (65–97) | 73 (54–88) | 79 (65–90) |
| Cine | 79 (58–93) | 88 (68–97) | 86 (65–97) | 81 (61–93) | 83 (70–93) |
| Combined interpretation | 88 (68–97) | 92 (73–99)* | 91 (72–99)* | 88 (69–97) | 90 (77–97)* |
| DCE + cine | 92 (73–99)* | 79 (58–93) | 81 (62–94) | 90 (70–99)* | 85 (72–94) |
| Rest + cine | 83 (63–95) | 79 (58–93) | 80 (59–93) | 83 (61–95) | 81 (67–91) |
| Rest + DCE | 83 (63–95) | 83 (63–95) | 83 (63–95) | 83 (63–95) | 83 (70–93) |
| Per vessel | |||||
| DCE | 56 (38–73) | 90 (83–95)* | 63 (44–80)* | 87 (79–92) | 82 (75–88) |
| Rest | 56 (38–73) | 89 (82–94) | 61 (42–78) | 87 (79–92) | 81 (74–87) |
| Cine | 65 (46–80) | 87 (80–93) | 61 (43–77) | 89 (81–94) | 82 (75–88) |
| Combined interpretation | 82 (65–93)* | 83 (74–89) | 60 (44–74) | 94 (87–98)* | 83 (75–88)* |
| DCE + cine | 71 (53–85) | 83 (74–89) | 56 (40–71) | 90 (83–95) | 80 (72–86) |
| Rest + cine | 74 (56–87) | 81 (72–88) | 54 (39–69) | 91 (83–96) | 79 (72–85) |
| Rest + DCE | 74 (56–87) | 85 (76–91) | 60 (43–71) | 91 (84–96) | 82 (75–88) |
| SPECT | 85 (69–95) | 97 (92–99) | 91 (75–98) | 96 (90–99) | 94 (89–98) |
PPV, positive predictive value; NPV, negative predictive value.
*
Highest value.