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. 2019 Oct 21;30(1):13–25. doi: 10.1111/bpa.12793

Figure 2.

Figure 2

Passive transfer models of NMO in mice (top) and rats (bottom) involving direct administration of AQP4‐IgG, sometimes together with human complement. As diagrammed, routes of administration have included direct injection into CNS tissues or peripherally, sometimes together with maneuvers to permeabilize the blood‐brain barrier. See text for explanations.