Table 2:

Hazard Ratios (95% CI) of losing HA status in the MHAS Mexican cohort^*

Basal characteristics	Crude			Adjusted
	HR	95% CI	P- value	HR	95% CI	P- value
Age	1.03	(1.03,1.04)	<0.01	1.03	(1.02, 1.03)	<0.01
Female	0.92	(0.87,0.97)	0.00	0.92	(0.86, 0.99)	0.02
Schooling	0.96	(0.96,0.97)	<0.01	0.97	(0.97, 0.98)	<0.01
Married	0.92	(0.87,0.98)	0.01	1.04	(0.97, 1.12)	0.30
Alcohol
Low-risk drinker	0.69	(0.63,0.77)	<0.01	0.81	(0.73, 0.91)	<0.01
Heavy drinker	0.73	(0.51,0.87)	0.04	0.82	(0.78, 1.12)	0.11
Smoker (ever)
Former	1.19	(1.11,1.27)	<0.01	1.16	(1.07, 1.25)	<0.01
Current	0.96	(0.89,1.04)	0.34	1.08	(0.99, 1.18)	0.09
Exercise	0.85	(0.8,0.91)	<0.01	0.9	(0.84, 0.96)	<0.01
Depression	1.23	(1.15,1.31)	<0.01	1.12	(1.04, 1.19)	<0.01
Overweight and obesity	1.22	(1.15,1.29)	<0.01	1.24	(1.16, 1.33)	<0.01
Low weight	0.96	(0.88,1.05)	0.42	0.91	(0.82, 1)	0.06
Long-lived mother	0.95	(0.88,1.01)	0.12	0.92	(0.85, 0.99)	0.02
Long-lived father	0.92	(0.86,0.98)	0.01	0.91	(0.85, 0.98)	0.01

^*Individuals aged 50 years and older