Table 2.

Antifungal activity of Satureja macrosiphon extracts against the fungal strains tested based on broth microdilution assay

Tested Candida and Aspergillus spp. isolate	Number of isolate	MIC (μL/mL) GM a (range)	MFC (μL/mL) GM a (range)
Candida spp. Standard isolate	C. albicans (6)	1.5 (1-2)	2.6 (2-4)
	C. dubliniensis (5)	2.2 (1-4)	3.6 (2-4)
	C. glabrata (5)	0.7 (0.5-1)	1.4 (1-2)
	C. tropicalis (1)	0.5	1.0
	C. parapsilosis (1)	4.0	4.0
	C. krusei (1)	0.25	1.0
Candida spp. azole-sensitive clinical isolates	C. albicans (9)	1.5(0.06-2)	2.7(1-4)
	C. dubliniensis (3)	1.1(0.5-2)	2.3(1-4)
	C. glabrata (1)	0.12	4.0
	C. tropicalis (2)	1.5(1-2)	1.5(1-2)
	C. parapsilosis (3)	0.5(0.25-1)	2.0
Candida spp. azole-resistant clinical isolates	C. albicans (12)	1.3(0.5-4)	1.9(0.5-4)
	C. dubliniensis (2)	0.25	2.0
	C. tropicalis (3)	2.5(1-4)	3.0(2-4)
Aspergillus spp. standard isolate	A. flavus (1 )	2.0	4.0
	A. fumigatus (2 )	1.1 (0.25-2.0)	2.5 (1-4)
	A. oryzae (1 )	2.0	4.0
	A. clavatus (1 )	0.25	0.5

GM: geometric mean, MIC: minimum inhibitory concentration, MFC: minimum fungicidal concentration