Skip to main content
. 2020 Feb 21;15(2):e0228806. doi: 10.1371/journal.pone.0228806

Fig 4. Serum antibody levels against A. actinomycetemcomitans according to the detection of the species and its serotype in saliva.

Fig 4

Serum IgA- (A) and IgG-class (B) antibodies against different serotypes (A–E) of A. actinomycetemcomitans were determined by ELISA. Presence of A. actinomycetemcomitans in saliva was detected using qPCR, and its serotype was determined by PCR designed for serotyping. The serotype of the antigen in the ELISA is presented on the x-axis separately for those whose saliva did not contain A. actinomycetemcomitans, for those having A. actinomycetemcomitans, but harbouring different serotype in saliva, and for those harbouring the same serotype in saliva. Number of samples was 198, the columns present the mean values with error bars showing the SE. The asterisks display the terms of linear trend between the groups according to ANOVA-test for logarithmically transformed ELISA-units; *** p<0.001, ** p<0.01.