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. Author manuscript; available in PMC: 2020 Feb 21.
Published in final edited form as: Eur Respir J. 2018 Oct 10;52(4):1801118. doi: 10.1183/13993003.01118-2018

Figure 3. Methionine oxidation, airway MPO and neutrophils are strong correlates of bronchiectasis in early CF.

Figure 3.

We tested the Spearman correlations of PRAGMA-%Dis and PRAGMA-%Bx with BALF measures (MetO, % OxMet, MPO, total protein), BAL cell populations [percentages of neutrophils (PMNs), macrophages (MΦ), lymphocytes (Lymphs) and eosinophils (Eos)], patient age (months), patient sweat chloride (mM) and the total number of antibiotic courses received by patients in the prior 12 months. (A) Blue-to-red heatmap of Spearman’s ρ for the indicated variables. Red = positive correlation, blue = negative correlation. The intensity of the color indicates the strength of the relationship. (B) Matching single-gradient white-to-red heatmap of p-values (expressed as −log(P)). Intensity of the red color indicates greater statistical significance. Black cells indicate results of p > 0.05 for the relevant pairwise correlation. Cells denoted by (X) indicate where rows and columns for the same variable meet.