Table 1.
Patient characteristics and clinical findings
| Childrena (n) | 24 |
| Age (months) | 31 ± 11 |
| Female:Male (n) | 16:8 |
| F508del homozygous (%) | 50.0 |
| Sweat chloride (mmol/l) | 92±28 |
| Pancreatic insufficiency (%) | 87.5 |
| Using antibiotics at BAL (%) | 91.2 |
| Past antibiotic coursesb | 2.9 ± 1.9 |
| Secondhand smoke (%) | 29.2 |
| BAL neutrophilsc (%) | 27.7 ± 18.9 |
| BAL macrophagesc (%) | 64.6 ± 19.7 |
| BAL lymphocytesc (%) | 7.2 ± 4.7 |
| BAL eosinophilsc (%) | 0.5 ± 0.8 |
| Positive BAL culture (%)c | 39.1 |
| Positive for S. aureus (%)c | 26.1 |
| Positive for P. aeruginosa (%)c | 4.3 |
Data are mean ± SD or a percentage.
a
All subjects received prospective BAL and CT procedures.
b
Number of antibiotic courses received (oral and/or i.v., including prophylaxis) 12 months prior to the prospective visit (n=18).
c
n=23.