Table 5. Composition of virulence genes of all sequence types combined and sequence type 191 according to isolation date or source of bacteremia.
| Genes | ST191 | ALL | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Source of bacteremia | Isolated year | Isolated year | |||||||
| Respiratory tract(n = 46) | Other(n = 13) | p-value | 2009-2012(n = 37) | 2013-2015(n = 22) | p-value | 2009-2012(n = 37) | 2009-2012(n = 37) | p-value | |
| Outer membrane vesicle | |||||||||
| A1S_0009 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| A1S_0116 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 50(92.6) | 39(88.6) | 0.37 |
| A1S_1180 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| A1S_1321 | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 53(98.1) | 44(100) | 0.55 |
| A1S_1386 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| A1S_1510 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 53(98.1) | 44(100) | 0.55 |
| A1S_1921 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| A1S_2470 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| A1S_2525 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| A1S_3143 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| A1S_3175 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| A1S_3411 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ACV72173.1 | 43(93.5) | 13(100) | 0.47 | 34(91.9) | 22(100) | 0.24 | 46(85.2) | 43(97.7) | 0.03 |
| ACV72174.1 | 43(93.5) | 13(100) | 0.47 | 34(91.9) | 22(100) | 0.24 | 47(87.0) | 43(97.7) | 0.06 |
| ADB23465.1 | 43(93.5) | 13(100) | 0.47 | 34(91.9) | 21(95.5) | 0.52 | 47(87.0) | 43(97.7) | 0.06 |
| ADB23466.1 | 39(84.8) | 12(92.3) | 0.43 | 31(83.8) | 20(90.9) | 0.36 | 40( | 39( | |
| ADB23467.1 | 43(93.5) | 12(92.3) | 0.64 | 34(91.9) | 21(95.5) | 0.52 | 47(87.0) | 42(95.5) | 0.14 |
| ADB23468.1 | 43(93.5) | 13(100) | 0.47 | 34(91.9) | 22(100) | 0.24 | 47(87.0) | 43(97.7) | 0.06 |
| ADB23470.1 | 43(93.5) | 13(100) | 0.47 | 34(91.9) | 22(100) | 0.24 | 47(87.0) | 43(97.7) | 0.06 |
| ADB23471.1 | 40(87.0) | 13(100) | 0.21 | 33(89.2) | 20(90.9) | 0.60 | 45(83.3) | 41(93.2) | 0.126 |
| ADB23472.1 | 37(80.4) | 12(92.3) | 0.29 | 28(75.7) | 21(95.5) | 0.07 | 41(75.9) | 40(90.9) | 0.04 |
| ADB23473.1 | 42(91.3) | 13(100) | 0.36 | 33(89.2) | 22(100) | 0.15 | 46(85.2) | 43(97.7) | 0.03 |
| GADB23474.1 | 43(93.5) | 13(100) | 0.47 | 34(91.9) | 22(100) | 0.24 | 46(85.2) | 43(97.7) | 0.03 |
| GADB23475.1 | 43(93.5) | 13(100) | 0.47 | 34(91.9) | 22(100) | 0.24 | 47(87.0) | 43(97.7) | 0.06 |
| blaOXA-24 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 0(0) | 0(0) | 1 |
| Antibiotic resistance | |||||||||
| ABUW_1156 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 53(98.1) | 40(90.9) | 0.12 |
| ABUW_1499 | 43(93.5) | 13(100) | 0.47 | 36(97.3) | 20(90.9) | 0.31 | 45(83.3) | 38(86.4) | 0.45 |
| ABUW_1520 | 41(89.2) | 13(100) | 0.27 | 35(94.6) | 19(86.4) | 0.26 | 45(83.3) | 26(59.1) | <0.01 |
| ABUW_1645 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_1672 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_1673 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 53(98.1) | 44(100) | 0.55 |
| ABUW_1692 | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 53(98.1) | 44(100) | 0.55 |
| ABUW_1755 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_1768 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_1849 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_1851 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_1966 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 0(0) | 0(0) | 1 |
| ABUW_2074 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_2550 | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 53(98.1) | 44(100) | 0.55 |
| Aromatic hydrocarbon metabolism | |||||||||
| ABUW_2090 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_2123 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_2236 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_2349 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_2370 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_2374 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| benP1 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| paaI1 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| paaY | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| pcaC | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| pcaD1 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| pcaU | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Transcriptional regulation | |||||||||
| ABUW_2520 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ABUW_2544 | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 52(96.3) | 44(100) | 0.30 |
| Immune evasion | |||||||||
| ACICU_00074 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ACICU_00075 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 12(27.3) | <0.01 |
| ACICU_00076 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 12(27.3) | <0.01 |
| ACICU_00077 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 12(27.3) | <0.01 |
| ACICU_00078 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 12(27.3) | <0.01 |
| ACICU_00079 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 12(27.3) | <0.01 |
| ACICU_00080 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 12(27.3) | <0.01 |
| ACICU_00081 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 1(2.3) | 0.25 |
| ACICU_00082 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 1(2.3) | 0.25 |
| ACICU_00083 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 1(2.3) | 0.25 |
| ACICU_00084 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 1(2.3) | 0.25 |
| ACICU_00085 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 4(7.4) | 1(2.3) | 0.25 |
| ACICU_00086 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 7(13.0) | 15(34.1) | 0.01 |
| ACICU_00087 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 7(13.0) | 15(34.1) | 0.01 |
| ACICU_00088 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ACICU_00089 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ACICU_00091 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ACICU_00092 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| lpsB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| lptE | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| lpxA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| lpxB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| lpxC | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| lpxD | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| lpxL | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| lpxM | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| eps | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 43(79.6) | 42(95.5) | 0.02 |
| pgi | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ptk | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ptp | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Regulation | |||||||||
| abaI | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 50(92.6) | 39(88.6) | 0.37 |
| abaR | 43(93.5) | 11(84.6) | 0.30 | 36(97.3) | 18(81.8) | 0.06 | 49(90.7) | 35(79.5) | 0.10 |
| bfmR | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| bfmS | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Killing of host cells | |||||||||
| abeD | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| envZ | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| fhaB | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 52(96.3) | 37(84.1) | 0.04 |
| fhaC | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 1(1.9) | 0(0) | 0.55 |
| Biofilm formation | |||||||||
| adeF | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| adeG | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| bap | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 53(98.1) | 40(90.9) | 0.12 |
| csuA | 44(95.7) | 13(100) | 0.61 | 37(100) | 20(90.9) | 0.14 | 47(87.0) | 36(81.8) | 0.33 |
| csuA/B | 44(95.7) | 13(100) | 0.61 | 37(100) | 20(90.9) | 0.14 | 47(87.0) | 35(79.5) | 0.23 |
| csuB | 44(95.7) | 13(100) | 0.61 | 37(100) | 20(90.9) | 0.14 | 47(87.0) | 35(79.5) | 0.23 |
| csuC | 44(95.7) | 13(100) | 0.61 | 37(100) | 20(90.9) | 0.14 | 47(87.0) | 36(81.8) | 0.33 |
| csuD | 44(95.7) | 13(100) | 0.61 | 37(100) | 20(90.9) | 0.14 | 47(87.0) | 36(81.8) | 0.33 |
| csuE | 44(95.7) | 13(100) | 0.61 | 36(97.3) | 20(90.9) | 0.31 | 46(85.2) | 36(81.8) | 0.43 |
| pgaA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 53(98.1) | 44(100) | 0.55 |
| pgaB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| pgaC | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 40(90.9) | 0.04 |
| pgaD | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 15(27.8) | 19(43.2) | 0.14 |
| adeH | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Antibiotic resisance | |||||||||
| adeI | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| adeJ | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| adeK | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| blaPER-1 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 3(5.6) | 1(2.3) | 0.39 |
| Transcriptional regulation | |||||||||
| alkR | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| gigA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| gigB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| gigC | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| soxR | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 53(98.1) | 44(100) | 0.55 |
| Iron uptake | |||||||||
| barA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| barB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basC | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basD | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basF | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basG | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basH | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basI | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| basJ | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| bauA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 40(90.9) | 0.04 |
| bauB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| bauC | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| bauD | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| bauE | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| bauF | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| nfuA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Porin | |||||||||
| carO | 46(100) | 11(84.6) | 0.046 | 37(100) | 20(90.9) | 0.14 | 54(100) | 40(90.9) | 0.04 |
| omp22 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| omp33-36 | 0(0.0) | 0(0.0) | 1 | 37(100) | 22(100) | 1 | 0 | 0 | |
| ompR | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| orpD | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Serun resistance, invasion | |||||||||
| cipA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| cobA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| pbpG | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| surA1 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| tuf | 46(10) | 13(100) | 1 | 36(97.3) | 22(100) | 0.63 | 53(98.1) | 44(100) | 0.55 |
| typA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | |||
| Enzyme | |||||||||
| plcC1 | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 8(14.8) | 14(31.8) | 0.05 |
| plcC2 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| plcD | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| pldA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Cysteine metabolism | |||||||||
| cysD | 46(10) | 13(100) | 1 | 54(100) | 44(100) | 1 | |||
| cysE | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| cysH | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| cysI | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| cysN | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| cysQ | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| sulP | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | |||
| Siderophore biosynthesis | |||||||||
| entA | 46(100) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 42(95.5) | 0.20 |
| Neutrophil influx | |||||||||
| gacS | 46(10) | 13(100) | 1 | 54(100) | 44(100) | 1 | |||
| paaA | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 53(98.1) | 44(100) | 0.55 |
| Type II protein secretion system | |||||||||
| gspD | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Type VI protein secretion system | |||||||||
| vgrG1 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 39(72.2) | 27(61.4) | 0.29 |
| vgrG2 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 52(96.3) | 33(75.0) | <0.01 |
| vgrG3 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 53(98.1) | 44(100) | 0.55 |
| vgrG4 | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 40(74.1) | 27(61.4) | 0.20 |
| hcp | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 12(22.2) | 15(34.1) | 0.14 |
| Type V protein secretion system | |||||||||
| ata | 41(89.1) | 12(92.3) | 0.60 | 31(83.8) | 22(100) | 0.08 | 42(77.8) | 39(88.6) | 0.13 |
| Stress response genes | |||||||||
| kef | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| kefF | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 54(100) | 44(100) | 1 |
| mscS | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| ostB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| recA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| resP | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| trkH | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| upsA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| uspA | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 0(0) | 0(0) | 1 |
| uvrD | 0(0.0) | 0(0.0) | 1 | 0(0.0) | 0(0.0) | 1 | 0(0) | 0(0) | 1 |
| Manganese acquisition system | |||||||||
| mumC | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 52(96.3) | 44(100) | 0.30 |
| mumT | 45(97.8) | 13(100) | 0.78 | 36(97.3) | 22(100) | 0.63 | 52(96.3) | 44(100) | 0.30 |
| Adherence | |||||||||
| ompA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| Micronutrient acquisition | |||||||||
| znuA | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| znuB | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| znuC | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
| zur | 46(10) | 13(100) | 1 | 37(100) | 22(100) | 1 | 54(100) | 44(100) | 1 |
Data are expressed as N (%). Values with statistical significance (p-value<0.05) are expressed in boldface.