Table 3.

Reasons for Switching and/or Discontinuing Biologic Originator or Biosimilar Treatment

	Adverse Events	Loss of Efficacy	Remission	Patient Preference	Other
Reason for Switching Treatment
Unweighted mean	23%	52%	N/A	14%	34%
Median	22%	53%	N/A	7%	34%
Range	2–63%	2.5–98%	N/A	1.9–44%	5–67%
Reason for Discontinuing Treatment*
Unweighted mean	25%	48%	10%	10%	18%
Median	23%	50%	4%	9%	15%
Range	4.4–77%	6.3–92%	0–52%	4–16%	2–55%

Note: *These data may or may not include patients switching treatment; not always evident from the reported information.

Abbreviation: N/A, not applicable.