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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Mol Neurobiol. 2019 Nov 9;57(2):1217–1232. doi: 10.1007/s12035-019-01781-9

Fig. 5. Vax1Lhrh-cre mice are infertile and lack GnRH expression.

Fig. 5

a IHC for GnRH on coronal sections in adulthood. Scale bar 100 μm. b A 20-week fertility study evaluating the number of litters born showed complete infertility of Vax1Lhrh-cre males and females. One-Way ANOVA, as compared to WT; *** p<0.001, n=3–5. c Estrus cycling was monitored daily in adult 14–18-week-old females. M, Metestrus; E, estrus; P, proestrus; D, diestrus. d Average cycle length in WT and Vax1Lhrh-cre females. n= 4–6. Statistical analysis by Student’s t-test; ** p<0.001.