Skip to main content
. Author manuscript; available in PMC: 2021 Feb 14.
Published in final edited form as: Circ Res. 2019 Dec 19;126(4):439–452. doi: 10.1161/CIRCRESAHA.119.315767

Figure 2: Blood pressure and vascular superoxide in wild-type and Sirt3OX mice in DOCA-salt model.

Figure 2:

(A) Systolic blood pressure was measured by telemetry before and after DOCA-salt treatment. Results are mean ± SEM. Blood pressure data were analyzed using 2-way ANOVA with repeated measurements. *P=0.03 vs WT+DOCA, n=7 in each group. (B) Aortic superoxide was measured by HPLC analysis of DHE-O2• specific product, 2-hydroxyethidium (2-OH-E+).12 Results are mean ± SEM (n=5). Data were analyzed using 2-way ANOVA and Bonferroni post-hoc multiple comparisons. *P<0.001 vs WT, **P<0.001 Sirt3OX+DOCA vs WT+DOCA.