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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2019 Aug 22;159(6):2216–2226.e2. doi: 10.1016/j.jtcvs.2019.06.103

TABLE 3.

Subgroup of patients with aortic diameter <45 mm who underwent no surgery versus those who underwent any ascending aortic intervention (isolated ascending aortic intervention or aortic valve replacement plus ascending aortic valve replacement) (n = 669)

Variable <45 mm and no surgery (n = 153) <45 and any ascending intervention (n = 516) P value
Aortic diameter (mm) 38.6 ± 4.3 38.4 ± 5.2 .788
Age (y) 61.5 ± 15.0 54.2 ± 13.2 <.001
Male sex 95 (62.1) 379 (73.5) .007
Height (cm)* 171.4 ± 10.9 173.8 ± 10.4 .055
Weight (kg) 83.5 ± 21.2 84.1 ± 19.0 .810
Body surface area (m2) 1.95 ± 0.25 1.98 ± 0.25 .369
Aortic cross-sectional area to height ratio (cm2/m)* 6.8 [±1.4] 6.8 ± 1.7 .789
Aortic regurgitation§ 25 (17.6) 221 (51.9) <.001
Aortic stenosis 33 (28.0) 218 (52.7) <.001
Mixed aortic regurgitation and stenosis 6 (5.3) 106 (26.4) <.001
Hypertension# 94 (61.4) 296 (65.5) .366
Smoking** 62 (43.1) 28 (7.7) <.001
Hyperlipidemia†† 73 (50.7) 189 (67.0) .001
Diabetes mellitus‡‡ 0 (0) 76 (17.6) .596
Coronary artery disease§§ 10 (11.5) 32 (15.0) .470
Stroke or TIA∥∥ 3 (4.6) 32 (10.4) .101
Turner syndrome¶¶ - 2 (3.1) N/A
Family history of aneurysm or dissection## - 9 (6.1) N/A
Marfan syndrome*** - 6 (2.1%) N/A

Values for continuous variables are presented as mean ± standard deviation, whereas values for categorical variables are presented as n (%). P values calculated by Student t test for continuous variables and χ2 test for categorical variables with n >5 or Fisher exact test for n ≤5. TIA, Transient ischemic attack. N/A, not available.

*

n = 476.

n = 470.

n = 458.

§

n = 568.

n = 532.

n = 584.

#

n = 605.

**

n = 507.

††

n = 426.

‡‡

n = 439.

§§

n = 301.

∥∥

n = 374.

¶¶

n = 64.

##

n = 148.

***

n = 289.