Table 3.
Summary of cryo-EM structures from glycoprotein–antibody complexes.
| Genus | Virus name | Antigen | Antibody | Fragment | EMD codes | Resolution (Å) |
|---|---|---|---|---|---|---|
| Lentivirus | Human immunodeficiency virus (HIV) | HIV-1 BaL virion | A12 | VHH | (Tomo) 5544/5551 | |
| m36 | VH | (Tomo) 5552/5553/5554/5555 | ||||
| 17b | IgG | (Tomo) 5456 | 22 | |||
| VRC01 | IgG | (Tomo) 5457 | 24 | |||
| VRC03 | IgG | (Tomo) 5458 | 23 | |||
| VRC02 | Fab | (Tomo) 5459 | 23 | |||
| VRC02 | IgG | (Tomo) 5460 | 25 | |||
| VRC01/17b | IgG | (Tomo) 5461 | 28 | |||
| b12 | Fab | (Tomo) 5018/5021 | 20/20 | |||
| 17b | Fab | (Tomo) 5020/5023 | 20/20 | |||
| 17b/A32 | Fab | 0466 | 13.08 | |||
| BG505 SOSIP.664 | 17b/8ANC195 | Fab | 7516/(Tomo) 3096 | 3.54/23 | ||
| 3BNC117 | Fab | 8644 | 4.4 | |||
| 3BNC117/PGT145 | Fab | 8643 | 4.3 | |||
| 3BC315 | Fab | 3067 | 9.3 | |||
| BG1/8ANC195 | Fab | 8693 | 6.2 | |||
| PG9/8ANC195 | Fab | 8695 | 11.5 | |||
| 3417 | Fab | 7552/7553/7554/7555/7556/7557 | 4.7/4.7/4.7/4.7/4.7/4.7 | |||
| VRC34.01 | Fab | 8125 | 17 | |||
| BF520.1 | Fab | 9166 | 4.8 | |||
| PGT128 | Fab | 3121/3120 | 4.36/4.47 | |||
| 17b | Fab | 8730 | 8.6 | |||
| PGV04 | Fab | 5779/5780/5781 | 5.8/7.9/8.2 | |||
| PGT151 | Fab | 9062 | 4.5 | |||
| BG505 DS-SOSIP.664 | vFP/VRC03/PGT122 | Fab | 7622/7621/7459/7460 | 4/4/3.8/3.6 | ||
| vFP | Fab | 8420/8421/8422 | 8.58/14.7/19.6 | |||
| PGT145 | Fab | 8427 | 6.8 | |||
| 2G12/VRC03 | Fab | 8981 | 8.8 | |||
| PGT122/VRC03/FP antibodies | Fab | 9189/20189/20191/9359/9320/9319/8977 | 3.8/4.3/3.5/3.7/4.2/4/3.18 | |||
| 462c SOSIP.664 | VRC01GL | Fab | 9294/9295/9303/9304 | 3.8/3.8/4.8/4.8 | ||
| B41 SOSIP. 664 | 17b | Fab | 8713 | 3.7 | ||
| PGV04 | Fab | 8716 | 7.4 | |||
| b12 | Fab | 8717 | 3.6 | |||
| 21c/8ANC195 | Fab | 9038 | 4.06 | |||
| PGT151 | Fab | 9030 | 6.7 | |||
| ZM197 SOSIP. 664 | VRC01 | Fab | 3059 | 9.32 | ||
| PC64M18C043 FL Env | PGT151 | Fab | 7858 | 3.1 | ||
| PGT151/PCT64-35S | Fab | 7859 | 6.8 | |||
| PC64M18C043 SOSIP. 664 | PGT151 | Fab | 7860 | 4.9 | ||
| PC64M4C054 SOSIP. 664 | PCT64-13C | Fab | 7863/7864/7089 | 5.1/30/13.2 | ||
| PCT64-13F | Fab | 7862 | 30 | |||
| PCT64-35S | Fab | 7865/7866 | 5.5/8.2 | |||
| PC64M4C054 FL Env | PGT151/PCT64-13C | Fab | 7861 | 30 | ||
| JR-FL EnvΔCT | PGT151 | Fab | 3308/3309 | 4.19/4.3 | ||
| PGT151/10E8 | Fab | 3312 | 8.8 | |||
| AMC011 SOSIP.v4.2 | PGV04 | Fab | 8302 | 6.2 | ||
| KNH1144 SOSIP. gp140 | VRC03 | Fab | 2484 | 6 | ||
| 17b | Fab | (Tomo) 5462 | 8.8 | |||
| Lymphocryptovirus | Epstein-Barr virus (EBV) | glycoprotein | AMMO1 | Fab | 7344/7345 | 4.8/10 |
| Betacoronavirus | Middle East respiratory syndrome-related coronavirus (MERS-CoV) | S protein | G4 | Fab | 8783/8784/8785/8786/8787/8788/8789/8790/8791/8792/8793 | 4/3.6/4.8/4.6/4.8/4.7/5/4.5/4/4/11.5 |
| LCA60 | Fab | 0401/0402 | 3.5/3.6 | |||
| Severe acute respiratory syndrome coronavirus (SARS-CoV) | S protein | S230 | Fab | 0403/0404 | 4.2/4.5 | |
| Alphainfluenzavirus | Influenza virus | Influenza virion | 6F12 | IgG | (Tomo) 6610/6611 | 25/25 |
| C179 | IgG | (Tomo) 5684/5685 | ||||
| 7B2 | IgG | (Tomo) 6612 | 25 | |||
| 3F5 | IgG | (Tomo) 6613/6614 | 25/25 | |||
| HA protein | K1915 | scFv | 8561/8562/8563/8564 | 4.8/4.8/4.8/4.8 | ||
| H7.5 | Fab | 9142/9143/9145 | 7.4/9.2/7.4 | |||
| Ebolavirus | Ebola virus (EBOV) | glycoprotein | 100/114 | Fab | 3310/3311 | 7.2/6.7 |
| c2G4/c13C6 | IgG/Fab | 8240 | 4.3 | |||
| c13C6/BDBV91 | IgG/Fab | 8241 | 5.5 | |||
| c4G7/c13C6 | IgG/Fab | 8242 | 4.3 | |||
| ADI-15878 | Fab | 8935/8936 | 4.14/4.29 | |||
| VLPs | c13C6 | IgG | (Tomo) 8226 | 25 | ||
| c2G4 | IgG | (Tomo) 8227 | 25 | |||
| c4G7 | IgG | (Tomo) 8228 | 25 |