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. 2020 Feb 21;10:3192. doi: 10.1038/s41598-020-60209-w

Table 4.

Multivariate hazard ratios of future MetS, diabetes, hypertension by serum calcium level.

Metabolic syndrome Diabetes mellitus Hypertension
Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
Events Events Events
HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value HR (95%CI) P value HR (95%CI) P value HR (95% CI) P value
Total N = 109 N = 53 N = 165
*1.67 (1.08–2.58) 0.021 *1.73 (1.07–2.79) 0.024 *2.23 (1.21–4.12) 0.010 *2.51 (1.30–4.83) 0.006 *1.50 (1.06–2.13) 0.023 *1.76 (1.22–2.55) 0.003
Male N = 86 N = 42 N = 129

*1.61

(1.03–2.50)

0.036

*1.76

(1.07–2.89)

0.027

*2.25

(1.21–4.19)

0.011

*2.86

(1.45–5.66)

0.003

1.35

(0.95–1.93)

0.096

*1.71

(1.17–2.50)

0.006
Female N = 23 N = 11 N = 36

*12.42

(3.39–45.49)

<0.001

*5.35

(1.14–25.03)

0.033

MetS, Metabolic syndrome; HR, Hazard ratio.

Model 1: Adjusted for age, gender and body mass index (BMI); Model 2: Adjusted for age, gender, BMI, total cholesterol, triglycerides, LDL-C, creatinine, uric acid, serum albumin, proteinuria, and smoking status.

Response variables: Incident MetS or diabetes or hypertension; Explanatory variables: Serum calcium level (mg/dL).

*Statistically significant variables (p value < 0.05).