Table 2.
Summary of the studies that highlight the association of allergic symptoms with dengue severity that were not eligible for the meta-analysis.
| Study | Allergic syndrome | Compared groups | ||||||
|---|---|---|---|---|---|---|---|---|
| Name | N | Value | Name | N | Value | P value | ||
| Koraka et al. (2003) in Indonesia (Values of total IgE and dengue-specific IgE in each groups were not described) | Dengue-specific IgE | Primary dengue infection | 41 | NR | Secondary Dengue Infection | 127 | NR | < 10−9 |
| “IgE reference serum” | 8 | NR | DHF | 30 | NR | 0.03 | ||
| “IgE reference serum” | 8 | NR | DSS | 67 | NR | 0.002 | ||
| “Non-dengue febrile illness and healthy controls” | 34 | NR | DF | 71 | NR | 0.4 | ||
| “Non-dengue febrile illness and healthy controls” | 30 | NR | DHF | 34 | NR | < 0.0001 | ||
| “Non-dengue febrile illness and healthy controls” | 34 | NR | DSS | 67 | NR | < 0.0001 | ||
| Total IgE (IU/mL) | “Non-dengue febrile illness and healthy controls” | 34 | NR | DF | 71 | NR | 0.8 | |
| Total IgE (IU/mL) | “Non-dengue febrile illness and healthy controls” | 34 | NR | DHF | 30 | NR | 0.539 | |
| Total IgE (IU/mL) | “Non-dengue febrile illness and healthy controls” | 34 | NR | DSS | 67 | NR | < 0.0001 | |
| Míguez-Burbano et al. (1999) in Colombia (Value: Mean ± SD) | Total IgE (IU/mL) | Dengue IgM sero (+) | 55 | 315.4 ± 19.9 | Dengue IgM sero (−) | 113 | 261.6 ± 5.9 | 0.016 |
| Dengue IgG sero (+) | 136 | 288.4 ± 5.9 | Dengue IgG sero ( −) | 32 | 192.6 ± 9.3 | 0.01 | ||
| Dengue IgG (+); IgM (−) | NR | 271.9 ± 8.5 | Dengue IgG (−); IgM (−) | NR | 192.6 ± 34 | 0.01 | ||
| Dengue IgG (+); IgM (+) | NR | 318.7 ± 1.3 | Dengue IgG (−); IgM (−) | NR | 192.6 ± 34 | 0.01 | ||
| Dengue IgG (−); IgM (+) | NR | 329.3 ± 1.3 | Dengue IgG (−); IgM (−) | NR | 192.6 ± 34 | 0.01 | ||
NR not reported.