Table 1.
Cardiopulmonary parameters
| Parameter | Control | Injured | Control | Injured | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C1 | C2 | C3 | C4 | I1 | I2 | I3 | I4 | I5 | I6 | Mean (SD) | Mean (SD) | |
| Weight (kg) | 30 | 33 | 30 | 33 | 30 | 28 | 29 | 33 | 31 | 31 | 31 (2) | 30 (2) |
| Lavage volume (L) | 0 | 0 | 0 | 0 | 4 | 5 | 2 | 4 | 9 | 2 | 0 (0) | 4 (3) |
| P/F ratio (mmHg) | 287 | 384 | 441 | 373 | 158 | 206 | 153 | 104 | 164 | 143 | 371 (64) | 154 (33)* |
| ABP (mmHg) | 65 | 78 | 89 | 79 | 68 | 95 | 97 | 97 | 75 | 62 | 78 (10) | 82 (16) |
| PAP (mmHg) | 20 | 27 | 14 | 20 | 34 | 27 | 27 | 20 | 32 | 34 | 20 (5) | 29 (6) # |
| CVP (mmHg) | 6 | 11 | 11 | 6 | 13 | 8 | 11 | 6 | 8 | 12 | 9 (3) | 10 (3) |
| HR (bpm) | 75 | 87 | 82 | 143 | 97 | 105 | 98 | 107 | 107 | 93 | 97 (31) | 101 (6) |
| CO (L/min) | 1.9 | 4.0 | 3.0 | 6.1 | 3.6 | 3.9 | 3.2 | 4.0 | 4.1 | 3.4 | 3.8 (1.8) | 3.7 (0.4) |
Abbreviations: C Control, I Injured (C1 to C4 and I1 to I6 refer to different animals), P/F ratio PaO2/FIO2 ratio sampled at PEEP 5 cmH2O, ABP mean arterial blood pressure, PAP Pulmonary arterial pressure, CVP Central venous pressure, HR Heart rate, CO Cardiac output measured by pulmonary artery flotation catheter thermodilution
*p < 0.001
#p = 0.02 from independent samples t test
Data are presented as mean (SD), where appropriate