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. Author manuscript; available in PMC: 2020 Feb 22.
Published in final edited form as: Acta Neuropathol. 2019 Apr 4;138(2):187–199. doi: 10.1007/s00401-019-02000-4

Figure 3. CD33 ITIM and ITIM-like Sequences Aligned to Consensus ITIM sequence.

Figure 3.

The CD33 ITIM and ITIM-like sequences (underlined) are shown relative to the ITIM consensus sequence of S/L/V/IxYxxL/V/I. Note that the CD33 ITIM-like sequence begins with a threonine, as opposed to the consequence S/L/V/I, and hence is relatively well-conserved with the consensus. The spacer between the ITIM and ITIM-like sequence in CD33 is 12 amino acids.