Table 8.
The majority of the studies examined involving disinfectants studied in the field of sterilization of the filling materials and the conclusions of each scientific work.
| First author and date | Journal | Title | Tested disinfectants | Conclusion/results |
|---|---|---|---|---|
| Grecca, 2011 [57] | Microscopy Research and Technique | SEM evaluation of thermoplastic endodontic materials alterations after disinfection: a new experimental model | 2.5% NaOCl and 2% CHX | Alteration of the surface of the gutta-percha cones |
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| Ôahinkesen, 2011 [61] | The Journal of Contemporary Dental Practice | Evaluation of residual antimicrobial effects and surface changes of gutta-percha disinfected with different solutions | 5.25% NaOCl, 2.5% NaOCl, 2% CHX, and 0.05% Octenisept | Exposing gutta-percha to 2% CHX for one minute was found to be the most effective method to eliminate the selected microorganisms |
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| Salvia, 2011 [59] | Brazilian Oral Research | Effectiveness of 2% peracetic acid for the disinfection of gutta-percha cones | 2% peracetic acid | After a 2.5 min exposure, 100% of the microbial inocula were eliminated |
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| Cleber, 2011 [48] | Australian Endodontic Journal | Effectiveness of different chemical agents for disinfection of gutta-percha cones | 1% NaOCl, 2% CHX, 10% povidone-iodine, and 0.9% saline solution | 2% chlorhexidine gluconate is the most efficient; saline solution is not efficient |
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| Attin, 2001 [51] | Journal of Endodontics | Antibacterial properties of electron beam-sterilized gutta-percha cones | Electron beam sterilization | The results of the present study could not demonstrate an influence of electron beam irradiation on the antibacterial properties of the gutta-percha cones |
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| Short, 2003 [60] | Journal of Endodontics | The crystallization of sodium hypochlorite on gutta-percha cones after the rapid-sterilization technique: an SEM study | 5.25% NaOCl | 96% ethyl alcohol, 70% isopropyl alcohol, and distilled water were able to remove chloride crystals that were formed on gutta-percha cones |
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| da Motta, 2001 [62] | International Endodontic Journal | Efficacy of chemical sterilization and storage conditions of gutta-percha cones | 2.5% NaOCl and 2.2% glutaraldehyde | 2.5% sodium hypochlorite and 2.2% glutaraldehyde proved to be effective sterilizing agents for gutta-percha cones, with sodium hypochlorite requiring a shorter period of use |
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| Gomes, 2005 [37] | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology | Disinfection of gutta-percha cones with chlorhexidine and sodium hypochlorite | CHX and 5.25% NaOCl | 5.25% NaOCl is an effective agent for the rapid disinfection of gutta-percha cones |
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| De Souza, 2003 [42] | Pesquisa Odontológica Brasileira | In vitro evaluation of different chemical agents for the decontamination of gutta-percha cones | 5.25% NaOCl, 10% polyvinylpyrrolidone-iodine, and paraformaldehyde tablets | Efficient for disinfection |
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| Prado, 2011 [49] | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology | The importance of final rinse after disinfection of gutta-percha and Resilon cones | 5.25% NaOCl, 2% CHX, and MTAD | Alteration of the surface of the gutta-percha cones after rinsing with distilled water |
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| Valois, 2005 [54] | Journal of Endodontics | Structural effects of sodium hypochlorite solutions on gutta-percha cones: atomic force microscopy study | 0.5%, 2.5%, or 5.25% NaOCl | Alterations of the topography or elasticity of the gutta-percha cone structure |
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| Roberta Redmersk, 2007 | Brazilian Journal of Microbiology | Disinfection of gutta-percha cones with chlorhexidine | 2% CHX | Decontamination of gutta-percha cones within a 5 min exposure |
| Gomes, 2007 [55] | Journal of Endodontics | Residual effects and surface alterations in disinfected gutta-percha and Resilon cones | 2% CHX, 5.25% NaOCl, and saline solution | No alteration of the cone surface |
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| Moller and Orstavik, 1985 [56] | Journal of Dental Research | Influence of antiseptic storage solutions on physical properties of endodontic gutta-percha points | 70% isopropyl alcohol, 5% chloramine, and 0.5% chlorhexidine | Linear dimensional changes |
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| Pang, 2007 [21] | Journal of Endodontics | Effects of short-term chemical disinfection of gutta-percha cones: identification of affected microbes and alterations in surface texture and physical properties | 5.25% NaOCl, 2% CHX, and ChloraPrep | Alteration of the surface of the gutta-percha cones and contamination of cones by Staphylococcus spp. |
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| Ozalp, 2006 [41] | Journal of Endodontics | The rapid sterilization of gutta-percha cones with sodium hypochlorite and glutaraldehyde | 2% glutaraldehyde or 2.5% NaOCl | 2% glutaraldehyde for 15 min is inefficient; 2.5% sodium hypochlorite is efficient |
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| Higgins, 1986 [43] | Journal of Endodontics | The use of paraformaldehyde powder for the sterile storage of gutta-percha cones | Paraformaldehyde power | Inefficient |
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| Montgomery, 1971 [38] | Oral Surgery, Oral Medicine, Oral Pathology | Chemical decontamination of gutta-percha cones with polyvinylpyrrolidone-iodine | Polyvinylpyrrolidone-iodine gamma rays | 6 min of PVP-I exposure was very effective for decontamination |
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| Royal, 2007 [40] | Journal of Endodontics | Comparison of 5.25% sodium hypochlorite, MTAD, and 2% chlorhexidine in the rapid disinfection of polycaprolactone-based root canal filling material | 5.25% NaOCl, MTAD, and 2% CHX | The results of this investigation show that 5.25% sodium hypochlorite, MTAD, and 2% chlorhexidine are all effective for the rapid disinfection of gutta-percha and Resilon |
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| Cardoso, 1998 [58] | Journal of Endodontics | Rapid sterilization of gutta-percha cones with glutaraldehyde | Glutaraldehyde (Glutaron II, Cidex 28, Glutalabor, Banicide, and Anti-G-Plus) | Sporicidal effect after a 15 min exposure |
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| Namazikhah, 2000 [63] | Journal of the California Dental Association | Gutta-percha: a look at the need for sterilization | Gutta-percha is not intentionally contaminated and needs decontamination before use | |
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| Subha, 2013 [45] | Journal of Endodontics | Efficacy of peracetic acid in rapid disinfection of Resilon and gutta-percha cones compared with sodium hypochlorite, chlorhexidine, and povidone-iodine | 1% peracetic acid, 3% NaOCl, 2% CHX, and 10% povidone-iodine | The outcome of this study confirmed the efficacy of 1% peracetic acid and 2% chlorhexidine in the rapid disinfection of both Resilon and gutta-percha |
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| Brito-Junior, 2012 [50] | Acta Odontologica Latinoamericana | Antibacterial activity of a plant extract and its potential for disinfecting gutta-percha cones | 2.5% NaOCl, 2.0% CHX, and Rosmarinus officinalis extract | Rosmarinus officinalis extract showed bactericidal effects against Enterococcus faecalis and the capacity to disinfect GP cones contaminated by it |
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| Lee, 1988 | Yonsei Medical Journal | An experimental study of the effect of the various antiseptic storage solutions on physical properties of gutta-percha cone | 70% isopropyl alcohol, 5% NaOCl, and 2.5% NaOCl | Alterations of the topography or elasticity of the gutta-percha cone structure |
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| Linke, 1983 [46] | Oral Surgery, Oral Medicine, Oral Pathology | Effective surface sterilization of gutta-percha points | 3% hydrogen peroxide, 95% ethanol, 4.5% NaOCl, and 17% Zephiran concentrate |
Efficient for decontamination |